The new Bayer 04 head coach Gerardo Seoane will welcome his squad for the start of the pre-season on 5 July. And now it is clear which opponents Charles Aránguiz and Co. will open the 2021/22 black and red season against: Last season's surprise team Union Berlin. That is followed by matches against Borussia Mönchengladbach, FC Augsburg and Borussia Dortmund.
The first meeting with champions Bayern Munich is on matchday eight in the middle of October and is followed a week later by the derby at FC Köln (22 to 24 October).
Bayer 04 finish 2021 with an away game at SC Freiburg just before Christmas. After the three-week break, league action returns on the weekend of 7 to 9 January with the home game against Union Berlin. The last match of the season for the Werkself is against SC Freiburg on 14 May.
Matchday 1, 14/15.8. (Return game: 7-9.1.22)
Union Berlin vs Bayer 04
Matchday 2, 20-22.8. (Return game: 14-16.1.22)
Bayer 04 vs Borussia Mönchengladbach
Matchday 3, 27.-29.8. (Return game: 21-23.1.22)
FC Augsburg vs Bayer 04
Matchday 4, 11/12.9. (Return game: 4-6.2.22)
Bayer 04 vs Borussia Dortmund
Matchday 5, 17-19.9. (Return game: 11-13.2.22)
VfB Stuttgart vs Bayer 04
Matchday 6, 24-26.9. (Return game: 18.-20.2.22)
Bayer 04 vs FSV Mainz 05
Matchday 7, 1-3.10. (Return game: 25-27.2.22)
Arminia Bielefeld vs Bayer 04
Matchday 8, 15-17.10. (Return game: 4-6.3.22)
Bayer 04 vs Bayern Munich
Matchday 9, 22-24.10. (Return game: 11-13.3.22)
FC Köln vs Bayer 04
Matchday 10, 29-31.10. (Return game: 18-20.3.22)
Bayer 04 vs VfL Wolfsburg
Matchday 11, 5-7.11. (Return game: 1-3.4.22)
Hertha BSC vs Bayer 04
Matchday 12, 19-21.11. (Return game: 8-10.4.22)
Bayer 04 vs VfL Bochum
Matchday 13, 26-28.11. (Return game: 16/17.4.22)
RB Leipzig vs Bayer 04
Matchday 14, 3-5.12. (Return game: 22-24.4.22)
Bayer 04 vs SpVgg Greuther Fürth
Matchday 15, 10-12.12. (Return game: 29/30.4.22)
Eintracht Frankfurt vs Bayer 04
Matchday 16, 14/15.12. (Return game: 6-8.5.22)
Bayer 04 vs TSG Hoffenheim
Matchday 17, 17-19.12. (Return game: 14.5.22)
SC Freiburg vs Bayer 04
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